This qualitative study conducted at District Lodhran, Punjab, Pakistan adopted a constructivist approach with an aim to investigate the social-cultural factors accelerating maternal mortality. The primary data was collected through in-depth interviews from 40 family members of deceased mothers and four focus group discussions, and the information for the secondary data pertaining to the victims of maternal death recorded in District Lodhran for the year 2016-17 was collected from the Health Department. The study concluded that there are various social and cultural practices, i.e. the practice of early marriages, repeated pregnancies with the wish of having a male child, treatment and living of pregnant women in the joint family system, and son’s preferences are the causative factors behind maternal mortality. The study recommends inculcation of awareness, especially among gestating women, regarding maternal health and associated factors, besides civil society’s measures for improvement and the government’s special attention towards the issue.