This paper attempts to explore the level of variations in the pattern of foreign policies of Pakistan and China to US Afghan strategy. To investigate this question, the paper examines US strategy in Afghanistan. The current administration under Trump and announcement of China Pakistan Economic Corridor further complicated the US presence in Afghanistan. The study analyses the factors that are responsible for differences between Pakistani and Chinese stance. About the results, China's response was an outcome of their foreign policy principles, that is not to indulge in direct clash with the US and Western world. The interests of China in Afghanistan are linked to that of Pakistan, South and Central Asia. China does not want to wage unilateral talks with Taliban at the cost of Pakistan's interests. While on the other hand, post 9/11 2001, Pakistan could not resist the pressure of US policies in Afghanistan because it was heavily dependent on the US, economically, militarily, politically and diplomatically. The respective Political structure and culture; their foreign policy priorities, goals, and tradition; perception of threat and resulting priorities; political and economic dependence; location, policy options and decision-making and professional capabilities of decision making were jointly responsible for their differences.