AI transformed healthcare communication. Conversational AI utilizes ChatGPT and other large language models more frequently. This technology finds personalized health data, expanding options. Intelligent technologies help people understand their health by teaching medical ideas and giving interactive support. AI improves patient care and workflow. AI improves patient-provider communication, raising legal, ethical, and regulatory issues. The research addresses these issues. This investigation identified studies that used PRISMA-compliant systematic reviews. A search of Google Scholar, Taylor & Francis, Elsevier, PubMed, and others yielded 50 hits. Native studies enable academics to evaluate AI in health communication as a whole. The studies identified issues related to ethical concerns, data privacy, and the preparation of healthcare professionals. The paper provides a health communication AI conceptual framework for planned, moral progress. AI must be invented,used, and applied equitably, responsibly, transparently, and ethically to maximize its revolutionary promise while respecting patient rights and promoting equitable public health.